El reflujo gástrico que provoca acidez estomacal es un factor de riesgo para el cáncer de faringe y laringe entre los no fumadores y no bebedores. Según un estudio de la Universidad de Brown, en Estados Unidos. Esa acidez aparece vinculada a un 78% más de riesgo de ambos cánceres.
El articulo en 20 minutos cita a la publicacion: http://intl-cebp.aacrjournals.org/
He buscado el citado articulo en el ejemplar de Mayo y Abril de dicha publicación y no está.
Tampoco he encontrado ninguna otra reseña sobre ese supuesto estudio.
¿fake?
Gastric Reflux Is an Independent Risk Factor for Laryngopharyngeal Carcinoma
Scott M. Langevin1,2, Dominique S. Michaud1, Carmen J. Marsit4,5, Heather H. Nelson6,7, Ariel E. Birnbaum3, Melissa Eliot1, Brock C. Christensen4,5, Michael D. McClean8, and Karl T. Kelsey1,2
+ Author Affiliations
Background: Gastric reflux can reach into the upper airway, inducing cellular damage in the epithelial lining. This condition is believed to be a risk factor for development of laryngopharyngeal squamous cell carcinoma (LPSCC), although the literature is conflicting.
Methods: To better clarify this relationship, we assessed the association of self-reported heartburn history and medication use among 631 patients with LPSCCs and 1234 control subjects (frequency-matched on age, gender, and town of residence) enrolled as part of a population-based case–control study of head and neck squamous cell carcinoma in the greater Boston area.
Results: After adjusting for age, gender, race, smoking, alcohol consumption, HPV16 seropositivity, education, and body mass index, subjects reporting a history of frequent heartburn and who were neither a heavy smoker nor heavy drinker had a significantly elevated risk of LPSCCs [OR, 1.78; 95% confidence interval (CI), 1.00–3.16]. Among those with a history of heartburn, there was an inverse association between antacid use and LPSCCs relative to those never taking heartburn medication (OR, 0.59; 95% CI, 0.38–0.93) that remained consistent when analyzed by smoking/drinking status, HPV16 status, or by primary tumor site.
Conclusions: Our data show that gastric reflux is an independent risk factor for squamous cancers of the pharynx and larynx. Further studies are needed to clarify the possible chemopreventive role of antacid use for patients with gastric reflux.
Comentarios
y Barret.
el otro día salio un en meneamoe un medico que recomendó un remedio para los vómitos
seguro que si le preguntamos a ese mismo nos recomendara lo mismo
Le recetó hacer sexo oral para acabar con sus problemas de vómitos
Le recetó hacer sexo oral para acabar con sus prob...
cronica.com.arEl articulo en 20 minutos cita a la publicacion: http://intl-cebp.aacrjournals.org/
He buscado el citado articulo en el ejemplar de Mayo y Abril de dicha publicación y no está.
Tampoco he encontrado ninguna otra reseña sobre ese supuesto estudio.
¿fake?
#3 Si buscas al autor en su base de datos te sale:
http://intl-cebp.aacrjournals.org/content/early/2013/05/21/1055-9965.EPI-13-0183.abstract?sid=3cf501fc-1ff2-47b9-9e2a-ec2d5737914b
Gastric Reflux Is an Independent Risk Factor for Laryngopharyngeal Carcinoma
Scott M. Langevin1,2, Dominique S. Michaud1, Carmen J. Marsit4,5, Heather H. Nelson6,7, Ariel E. Birnbaum3, Melissa Eliot1, Brock C. Christensen4,5, Michael D. McClean8, and Karl T. Kelsey1,2
+ Author Affiliations
Background: Gastric reflux can reach into the upper airway, inducing cellular damage in the epithelial lining. This condition is believed to be a risk factor for development of laryngopharyngeal squamous cell carcinoma (LPSCC), although the literature is conflicting.
Methods: To better clarify this relationship, we assessed the association of self-reported heartburn history and medication use among 631 patients with LPSCCs and 1234 control subjects (frequency-matched on age, gender, and town of residence) enrolled as part of a population-based case–control study of head and neck squamous cell carcinoma in the greater Boston area.
Results: After adjusting for age, gender, race, smoking, alcohol consumption, HPV16 seropositivity, education, and body mass index, subjects reporting a history of frequent heartburn and who were neither a heavy smoker nor heavy drinker had a significantly elevated risk of LPSCCs [OR, 1.78; 95% confidence interval (CI), 1.00–3.16]. Among those with a history of heartburn, there was an inverse association between antacid use and LPSCCs relative to those never taking heartburn medication (OR, 0.59; 95% CI, 0.38–0.93) that remained consistent when analyzed by smoking/drinking status, HPV16 status, or by primary tumor site.
Conclusions: Our data show that gastric reflux is an independent risk factor for squamous cancers of the pharynx and larynx. Further studies are needed to clarify the possible chemopreventive role of antacid use for patients with gastric reflux.
Impact: Elucidation of additional risk factors for head and neck cancer can allow for risk stratification and inform surveillance of high-risk patients. Cancer Epidemiol Biomarkers Prev; 22(6); 1–8. ©2013 AACR.
Received February 15, 2013.
Revision received March 28, 2013.
Accepted April 5, 2013.